Addiction | 4 min read
Medically Reviewed By
On July 22, 2025
Written By
On March 26, 2019
In our fast-paced, high-pressure society, some individuals may turn to substance use as a way to unwind, but this can carry risks, especially when it becomes habitual or leads to harmful consequences. But when does casual substance use cross the line into problematic use or substance abuse?
Understanding the differences between substance use, substance abuse, dependence, and addiction is important to know when to seek help. If you or someone you know is struggling, recognizing the signs and seeking treatment early can get you on a path to healing.
Substance use refers to the casual or occasional use of drugs or alcohol. This may be drinking a glass of wine at dinner, having a beer after work, or taking a prescribed medication as directed. Not all substance use is harmful, but when its use leads to negative consequences, it crosses the line into substance abuse.
Substance abuse refers to a pattern of substance use that leads to significant impairment or distress, as defined in clinical criteria like those in the DSM-IV; this concept has been replaced by ‘substance use disorder’ in the DSM-5. This can include using a substance:
Common signs of substance abuse include:
In older classifications like the DSM-IV, substance abuse and substance dependence were distinct diagnoses; however, the DSM-5 combines them under ‘substance use disorder,’ which considers both behavioral patterns and physiological dependence. Dependence can develop in people who use substances responsibly or with substances that aren’t associated with drug abuse or drug addiction.
The two types of dependence are:[1]
Dependence can occur with medications like antidepressants or corticosteroids, even though these drugs are not typically associated with substance use disorders.[2] Having drug dependence doesn’t always mean you’re addicted, but it can be a component of addiction, particularly with drugs of abuse.
Addiction is a chronic, relapsing disorder characterized by compulsive substance use despite harmful consequences, involving neurobiological changes that affect reward, motivation, memory, and related circuitry.
According to the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-5), some of the signs of addiction, or substance use disorder, include:[3]
There’s no clear line or moment when recreational drug use crosses into addiction. Risk factors, use patterns, and consequences are more important. If substance use causes problems in your relationships, school or work responsibilities, or health, it’s time to evaluate your behaviors.
Are you lying about your alcohol abuse or hiding it? Are you isolating yourself or shifting your social circles, spending more time with people who also engage in drug misuse? Are you shirking your responsibilities because of substance use? Is substance use a means of escape or coping with difficult emotions?
There can be physical signs of substance abuse as well, including sudden changes in mood or appearance, fatigue or agitation, and withdrawal symptoms if you stop or cut back on substance use. Generally, if you’re questioning whether your substance use is a problem, it’s worth giving it more consideration.
Seeking help for substance use can be challenging, but it’s one of the most important steps to take for your health. Professional addiction treatment offers structured, personalized care that can get to the root causes of addiction and help you reach recovery.
Some of the available addiction treatment services include:
If you or a loved one is currently living with substance abuse and seeking evidence-based addiction services, help is available. Taking the first step now puts you on a path to holistic recovery and healthier living.
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The terms drug abuse and substance abuse are often used interchangeably, but addiction is a distinct condition involving compulsive use despite harm. Substance use refers to the casual or prescribed use of drugs or alcohol, while substance abuse is a harmful and nonmedical use of a substance that may lead to negative consequences. Addiction is a chronic medical condition that involves the compulsive use of substances, despite the problems it causes.
If you or a loved one can’t stop using substances like cannabis, alcohol, or opioids despite repeated attempts, experience withdrawal symptoms when trying to quit, or struggle with work, relationships, or legal issues due to substance use, or rely on substances to cope with stress, anxiety, or trauma, it may be time for professional addiction treatment and support.
Substance abuse is the harmful use of substances, including illicit drugs, prescription drugs, or alcohol, that can lead to negative consequences. Substance dependence involves physical or psychological reliance on a substance, leading to withdrawal symptoms if you try to cut back or stop.
Here at Ascendant New York, we understand the importance of having access to accurate medical information you can trust, especially when you or a loved one is suffering from addiction. Find out more on our policy.
[1] Psychological dependence: EBSCO. EBSCO Information Services, Inc. | www.ebsco.com. (n.d.). https://www.ebsco.com/research-starters/psychology/psychological-dependence
[2] Szalavitz, M., Rigg, K. K., & Wakeman, S. E. (2021, December). Drug dependence is not addiction-and it matters. Annals of medicine. https://pmc.ncbi.nlm.nih.gov/articles/PMC8583742/
[3] What is a substance use disorder?. Psychiatry.org – What Is a Substance Use Disorder? (n.d.). https://www.psychiatry.org/patients-families/addiction-substance-use-disorders/what-is-a-substance-use-disorder
[4] Highlights for the 2023 National Survey on Drug Use and … (n.d.-a). https://www.samhsa.gov/data/sites/default/files/NSDUH%202023%20Annual%20Release/2023-nsduh-main-highlights.pdf
[5] Centers for Disease Control and Prevention. (2025, May 14). U.S. overdose deaths decrease almost 27% in 2024. Centers for Disease Control and Prevention. https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2025/20250514.htm
[6] U.S. Department of Health and Human Services. (2024, October 3). Co-occurring disorders and health conditions. National Institutes of Health. https://nida.nih.gov/research-topics/co-occurring-disorders-health-conditions#mental
[7,8] Substance abuse and addiction statistics [2025]. NCDAS. (2025, July 7). https://drugabusestatistics.org/